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"TEL AVIV, ISRAEL — Viagra, the little blue pill traditionally associated with romantic optimism, awkward late-night adverts and couples who somehow own outdoor bathtubs, may have discovered an entirely different calling. Researchers report that sildenafil, Viagra’s active ingredient, could interfere with the ability of cancer cells to spread by disrupting how they access cholesterol. The research involved cancer cells, mouse models and roughly twenty years of health records from five million members of Israel’s Clalit Health Services. The human evidence identified an association rather than proving cause and effect, in line with coverage from bodies such as the NHS."
"The pharmaceutical industry immediately congratulated Viagra on becoming the first medication to maintain three completely different CVs without being accused of padding them out."
"Originally investigated for cardiovascular trouble, sildenafil became famous after researchers noticed that trial volunteers were suspiciously reluctant to hand back their unused medication. It went on to dominate the erectile dysfunction market, transformed late-night telly and gave the nation the phrase “consult your GP” moments before showing two pensioners strolling toward a suspiciously private caravan."
"Scientists now suggest the same biochemical pathway responsible for increasing blood flow may also interfere with cholesterol transport inside cancer cells. Cancer cells need cholesterol to build membranes, migrate and set up shop elsewhere in the body. Sildenafil increases a signalling molecule called cGMP, which researchers found can interfere with a protein responsible for moving cholesterol within cells — a mechanism broadly consistent with cancer metabolism research published by groups such as Cancer Research UK."
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Viagra Discovers It May Fight Cancer, Immediately Demands Promotion From Bedroom Pill to National Treasure
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