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• ↓ Latest News
• ↓ Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration
• ↓ De Novo Protein Design Overcomes Gene Editing Limits to Sustain CAR-T and TCR-T Cell Function
• ↓ New OpenBind-0 model and dataset benchmark co-folding tools in drug discovery
• ↓ Integrating Mass Spectrometry Restraints into Rosetta and AlphaFold Modeling Pipelines
• ↓ Brazil’s Largest Open Science Event Introduces Thousands to Protein Design with Foldit
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"Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery."

"Key Takeaways By combining Rosetta-based motif grafting with deep-learning tools like RFdiffusion, ProteinMPNN, and AlphaFold2,…"

"Key Takeaways De novo designed proteins bind and modulate entire target families simultaneously, bypassing the…"

"Key Takeaways OpenBind-0 (OB0) is a fully open-source co-folding model built on OpenFold3, trained on…"

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Latest News

Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration

De Novo Protein Design Overcomes Gene Editing Limits to Sustain CAR-T and TCR-T Cell Function

New OpenBind-0 model and dataset benchmark co-folding tools in drug discovery

Integrating Mass Spectrometry Restraints into Rosetta and AlphaFold Modeling Pipelines

Brazil’s Largest Open Science Event Introduces Thousands to Protein Design with Foldit